The AI that checks its science before it writes a single word.
Every VarsaAI output begins with VeriCore™ — a mandatory verification layer that cross-references every scientific entity against the world's leading life sciences databases before generation begins.
AI hallucinations in pharma aren't a nuisance. They're a liability.
Generic AI models generate scientific content confidently — and incorrectly. In regulated industries, an inaccurate receptor orientation or inverted pathway isn't an error that gets corrected in post. It goes to MLR, to HCPs, to patients.
44%
of organisations experienced negative consequences from GenAI use — with average losses of $4.4M per incident in pharma and healthcare.
18%
of AI-generated clinical summaries contained incomplete or misleading information (JAMA Network Open, 2023).
How VeriCore™ works.
Five sequential verification steps, each a hard gate. A partial pass is treated identically to a full fail. No generation begins until all five return PASS.
Scientific Entity Extraction
VeriCore™ parses the content brief and extracts every named scientific entity — drugs, receptors, cytokines, cell types, pathways, organelles, molecular interactions, and biological processes. Each entity is assigned a type classification before any lookup begins.
Primary Database Verification
For each extracted entity, VeriCore™ queries primary scientific databases. Protein structures against RCSB PDB. Sequences and domain architecture against UniProt/Swiss-Prot. Pathway node order and directionality against Reactome and KEGG. Drug names and mechanism classifications against WHO INN and FDA label databases.
Interaction & Binding Verification
Every molecular interaction is confirmed — binding interface, domain of each molecule involved, conformational consequence, downstream signalling, and directional accuracy. Any interaction that cannot be confirmed halts generation.
Pathway Sequence & Scale Verification
Signalling cascades validated against Reactome canonical node order. Every step is directionally correct, no steps inverted or conflated, and drug intervention at the correct node. Molecular scale consistency verified per scene.
Cell Morphology & Visual Convention Verification
Every cell type is verified against atlas-level morphological data. Nucleus-to-cytoplasm ratio, surface marker expression, and functional state indicators confirmed. Published visual conventions enforced from peer-reviewed journals.
The databases VeriCore™ trusts.
Primary peer-reviewed scientific databases — not training data, not generalised knowledge. Every verification traceable to a specific entry and published source.
RCSB Protein Data Bank
Experimentally determined protein structures — crystal structure, resolution, binding domain architecture and depositing publication.
UniProt / Swiss-Prot
Canonical protein sequence and functional annotation — domain architecture, PTMs, subcellular localisation and isoforms.
Reactome
Peer-reviewed human pathway database providing canonical node order, reaction types, and directional specificity for all signalling cascades.
KEGG Pathway
Comprehensive metabolic and signalling pathway maps cross-referenced with Reactome. Authoritative for metabolic pathways and drug-target mapping.
WHO INN / FDA Label / EMA SmPC
Authoritative sources for drug name, molecular class, target and approved mechanism statements before any appearance in output.
Nature Reviews · Cell · PNAS
Peer-reviewed published review figures used for visual convention verification of pathways, cell types and molecular interactions.
What VeriCore™ checks on every generation.
Drug structure & class
INN name, molecular class (mAb, small molecule, ADC, mRNA-LNP, CAR-T), structural representation and mechanism interaction type.
Receptor topology
Membrane topology, extracellular domain structure, active/inactive conformational states, glycosylation status.
Binding interfaces
Domain-to-domain contacts, conformational consequence, downstream signalling, activating or inhibitory directionality.
Pathway sequence
Canonical upstream-to-downstream node order confirmed against Reactome and KEGG. Drug intervention at the correct cascade node.
Cell morphology
Correct size, shape, nucleus-to-cytoplasm ratio, surface markers and functional state for every cell type.
Scale consistency
Biologically plausible relative scale between co-depicted entities — antibody, receptor, cytokine, cell, organelle.
Terminology & pronunciation
Pathway names in canonical form. WHO INN drug names. TTS pronunciation verified against IPA phoneme standards.
Structural prohibitions
Scientifically incorrect representations are enforced as negative constraints in image generation — errors never reach output.
Every output ships with a VeriCore™ record.
The structured audit trail is designed to be the document your MLR reviewer needs. No black boxes. Every claim linked to its source.
{
"vericore_status": "VERICORE_PASSED",
"generated_at": "2025-11-12T09:43:17Z",
"entity_audit": {
"pembrolizumab": {
"visual_class": "IgG4_Y_shaped_monoclonal_antibody",
"pdb_reference": "PDB 5DK3",
"confidence": "HIGH"
},
"PD-1_receptor": {
"pdb_reference": "PDB 5IUS",
"binding_interface_verified": true,
"confidence": "HIGH"
}
},
"pathway_audit": {
"JAK_STAT_signalling": {
"reactome_id": "R-HSA-6785807",
"node_order_verified": true,
"drug_intervention_point": "Node 1"
}
},
"approval_status": "READY_FOR_MLR_REVIEW"
}The right answer for every team.
Medical Affairs Directors & VPs
You are accountable for the scientific accuracy of everything your team produces. VeriCore™ extends that accountability to every AI-assisted output — without slowing your team down.
- →Every entity cross-referenced against PDB, UniProt, Reactome and KEGG before a word is written
- →The VeriCore™ audit trail is the document your MLR reviewer needs
- →Stage 0 is a blocking gate — unverified content does not proceed
- →When the science changes, regeneration runs VeriCore™ again
Accuracy you can measure.
Primary scientific databases verified on every generation
Sequential verification steps — all mandatory, all blocking
Entity type classifications checked per content brief
Unverified entities that reach content generation
Ready to see the AI that checks its science before you do?
Book a 25-minute live demo. We'll run VeriCore™ on a compound from your therapeutic area and show you the audit trail in real time.